Domperidone (Generic of Motilium)

Domperidone is not in the same family of medication as cisapride. Another, related, but older medication, metoclopramide (Maxeran™), is also known to increase milk production, but it has frequent side effects which have made its use for many nursing mothers unacceptable (fatigue, irritability, depression). Domperidone is a dopamine antagonist but is less likely than metoclopramide to produce extra pyramidal side effects since it does not cross the blood brain barrier. It stimulates gastro-intestinal mobility and is used in the management of nausea and vomiting. Domperidone has been shown to possess cardiac electrophysiological effects such as prolongation of cardiac repolarisation at normal doses. Examples of CYP3A4 inhibitors include azole antifungals, macrolide antibiotics (e.g.

Domperidone's primary disadvantage is its restricted availability. Metoclopramide, while not FDA approved for lactation augmentation, is approved for other conditions including diabetic gastroparesis and GERD. Domperidone drug should pass any customs house, including American, without problems. If you have problems with customs house, inform pharmacy, they shall repeat (free-of-charge) your Motilium order. Domperidone must never be used as the first approach to correcting breastfeeding difficulties. Domperidone is not a cure for all things.

MOTILIUM suppresses the peripheral effects (digestive disorders, nausea and vomiting) of dopaminergic agonists. Since MOTILIUM has gastro-kinetic effects, it could influence the absorption of concomitant orally administered medicines, particularly those with sustained release or enteric coated formulations. Motilium (Domperidone) is a medicine that increases the movements or contractions of the stomach and bowel. Domperidone is also used to treat nausea and vomiting caused by other drugs used to treat Parkinson's Disease. Motilium ( dom-PER-i-done) is a medicine that increases the movements or contractions of the stomach and bowel. Motilium is also used to treat nausea and vomiting caused by other drugs used to treat Parkinson's Disease.

Patients on prolonged therapy should be reviewed regularly. They should be taken after meals and not before meals, ie. Patients on prolonged therapy should be reviewed regularly.